Visual diseases

This NVRI research program is committed to undertaking clinically oriented vision research, including public eye health, aimed at improving the health and well-being of the community.

Eye biomarkers for neurodegenerative diseases

Related NVRI projects investigate neuronal and non-neuronal tissues of the eye using advanced ophthalmic imaging modalities such as in vivo confocal microscopy, retinal photography and tomographic techniques. The aim is characterise microstructural alterations specific to two major neurodegenerative conditions; Alzheimer’s diseases (AD) and diabetic peripheral neuropathy and identify eye changes which might pre-date brain changes in AD or peripheral nerve damage in diabetic neuropathy, and thus represent a quick, easy, non-invasive method for early detection and monitoring of these diseases.

Ocular microvasculature in systemic diseases

This research focuses on investigating in vivo conjunctival and retinal microvasculature in systemic diseases e.g. hypertension and diabetes by the characterization of subtle and specific vascular alterations (structural and architectural) that may help identifying early stages of the disease, subsequent development to overt phase and monitoring their progression/regression.

Eye screening and tele-ophthalmology

The NVRI conducts research to assess the effectiveness of eye screening programs and tele-ophthalmology for early detection of two major eye conditions; diabetic retinopathy (DR) and age-related macular degeneration (AMD) in high risk populations.